A new video shows flames emanating from one side of a Boeing 767 moments after takeoff, reports LiveMint.com. "Delta flight 446 was forced to make an emergency landing in Los Angeles," they report, adding "No one was injured. The fire was extinguished upon landing." According to a report by Aviation A2Z, the plane (24-year-old Boeing 767-400 with registration N836MH) had just departed from Los Angeles International Airport when its left engine ignited. The pilots promptly declared an emergency and requested to return to the airport. Delta faced a similar issue less than three months ago. The article notes the engine of an Airbus also caught on fire in April when pushing back from the gate for departure. CBS News describes that incident: Delta said crew members evacuated the cabin when flames were seen in the tailpipe of one of the plane's two main engines and fire crews quickly responded. According to Delta, the plane, an Airbus 330, had 282 passengers, 10 flight attendants and two pilots on board... The engine fire marks the latest aviation scare involving the airline in recent months. In February, 21 people were injured after a Delta plane flipped upside down while landing amid wintry conditions at Toronto Pearson International Airport. All of the injured passengers were later released from the hospital. In January, several people were injured after a Delta flight aborted its takeoff at Hartsfield-Jackson Atlanta International Airport, forcing about 200 passengers to evacuate the plane through emergency slides. ["A passenger says the engine on the Boeing 757 caught fire," according to CBS's video report in January.]

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San Francisco-based startup Orchid Health "screens embryos for thousands of potential future illnesses," reports the Washington Post, calling it "the first company to say it can sequence an embryo's entire genome of 3 billion base pairs." It uses as few as five cells from an embryo to test for more than 1,200 of these uncommon single-gene-derived, or monogenic, conditions. The company also applies custom-built algorithms to produce what are known as polygenic risk scores, which are designed to measure a future child's genetic propensity for developing complex ailments later in life, such as bipolar disorder, cancer, Alzheimer's disease, obesity and schizophrenia. Orchid, [founder Noor] Siddiqui said in a tweet, is ushering in "a generation that gets to be genetically blessed and avoid disease." Right now, at $2,500 per embryo-screening on top of the average $20,000 for a single cycle of IVF, Siddiqui's social network in Silicon Valley and other tech hubs is an ideal target market... Yet several genetic scientists told The Post they doubt Orchid's core claim: that it can accurately sequence an entire human genome from just five cells collected from an early-stage embryo, enabling it to see many more single- and multiple-gene-derived disorders than other methods have. Experts have struggled to extract accurate genetic information from small embryonic samples, said Svetlana Yatsenko, a Stanford University pathology professor who specializes in clinical and research genetics. Genetic tests that use saliva or blood samples typically collect hundreds of thousands of cells. For its vastly smaller samples, Orchid uses a process called amplification, which creates copies of the DNA retrieved from the embryo. That process, Yatsenko said, can introduce major inaccuracies. "You're making many, many mistakes in the amplification," she said, rendering it problematic to declare any embryo free of a particular disease, or positive for one. "It's basically Russian roulette...." Numerous fertility doctors and scientists also told The Post they have serious reservations about screening embryos through polygenic risk scoring, the technique that allows Orchid and other companies to predict future disease by tying clusters of hundreds or even thousands of genes to disease outcomes and in some cases to other traits, such as intelligence and height. The vast majority of diseases that afflict humans are associated with many different genes rather than a single gene... And for traits such as intelligence, polygenic scoring has almost negligible predictive capacity — just a handful of IQ points... Or parents might select against an unwanted trait, such as schizophrenia, without understanding how they may be screening out desired traits associated with the same genes, such as creativity... The American College of Medical Genetics and Genomics calls the benefits of screening embryos for polygenic risks "unproven" and warns that such tests "should not be offered" by clinicians. A pioneer of polygenic risk scores, Harvard epidemiology professor Peter Kraft, has criticized Orchid, saying on X that "the science doesn't add up" and that "waving a magic wand and changing some of these variants at birth may not do anything at all." The article notes several startups are already providing predictions on intelligence. "In the United States, there are virtually no restrictions on the types of genetic predictions companies can offer, and no external vetting of their proprietary scoring methods."

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Fast Company's tech editor Harry McCracken (also harrymccSlashdot reader #1,641,347) writes: As part of Fast Company's "1995 week", I wrote about IBM's ThinkPad 701, the famous model with an expanding "butterfly" keyboard [which could be stretched from 9.7-inches to 11.5 inches]. By putting full-sized keys in a subnotebook-sized laptop, it solved one of mobile computing's biggest problems. IBM discontinued it before the end of the year, and neither it nor anyone else ever made anything similar again. And yet it remains amazing. Check out this 1995 ad for the keyboard! The article calls the butterfly ThinkPad "one of the best things the technology industry has ever done with moving parts," and revisits 1995's race "to design a subnotebook-sized laptop with a desktop-sized keyboard." It's still comically thick, standing almost as tall as four MacBook Airs stacked on each other. That height is required to accommodate multiple technologies later rendered obsolete by technological progress, such as a dial-up fax/modem, an infrared port, two PCMCIA expansion card slots, and a bulky connector for an external docking station... Lifting the screen set off a system of concealed gears and levers that propelled the two sections of keyboard into position with balletic grace... A Businesweek article cited sales of 215,000 units and said it was 1995's best-selling PC laptop. Yet by the time that story appeared in February 1996, the 701 had been discontinued. IBM never made anything like it again. Neither did anyone else... As portable computers became more popular, progress in display technology had made it possible for PC makers to use larger screens. Manufacturers were also getting better at fitting a laptop's necessary components into less space. These advances let them design a new generation of thin, light laptops that went beyond the limitations of subnotebooks. Once IBM could make a lightweight laptop with a wider screen, "the need for an expanding keyboard was no longer essential," says [butterfly ThinkPad engineer] George Karidis. "It would have just been a novelty." The article notes a fan's open source guides for repairing butterfly Thinkpads at Project Butterfly, and all the fan-community videos about it on YouTube, "from an excellent documentary to people simply being entranced by it. "As a thing of wonder, it continues to transcend its own obsolescence."

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Feature work on Plasma 6.5 this week includes "a major visual change that has been years in the wanting," according to the KDE blog: "rounded bottom corners for windows!" Neowin reports: This visual refresh, planned for the upcoming Plasma 6.5, is a feature that many users have been asking for over a long period, with a formal proposal even being submitted back in 2021. Its official arrival will mean less need for community-developed workarounds like kde-rounded-corners, a popular third-party script that has served this purpose for years. The feature will be enabled by default, but it includes an option for those who prefer the classic, sharp-cornered look.

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